Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Casp3  caspase 3   (Synonyms: A830040C14Rik, AC-3, Apopain, Caspase-3, CC3, CPP32, mldy, Yama)
Results	Reference
1	J:237195 Bosch PJ, Fuller LC, Sleeth CM, Weiner JA, Akirin2 is essential for the formation of the cerebral cortex. Neural Dev. 2016 Nov 21;11(1):21
1	J:90572 Cowan CM, Roskams AJ, Caspase-3 and caspase-9 mediate developmental apoptosis in the mouse olfactory system. J Comp Neurol. 2004 Jun 14;474(1):136-48
1	J:196028 Dillon CP, Oberst A, Weinlich R, Janke LJ, Kang TB, Ben-Moshe T, Mak TW, Wallach D, Green DR, Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep. 2012 May 31;1(5):401-7
1	J:193400 Domyan ET, Branchfield K, Gibson DA, Naiche LA, Lewandoski M, Tessier-Lavigne M, Ma L, Sun X, Roundabout receptors are critical for foregut separation from the body wall. Dev Cell. 2013 Jan 14;24(1):52-63
1*	J:306253 Flemmer RT, Connolly SP, Geizer BA, Opferman JT, Vanderluit JL, The Role of Mcl-1 in Embryonic Neural Precursor Cell Apoptosis. Front Cell Dev Biol. 2021;9:659531
1	J:296752 Fogarty LC, Flemmer RT, Geizer BA, Licursi M, Karunanithy A, Opferman JT, Hirasawa K, Vanderluit JL, Mcl-1 and Bcl-xL are essential for survival of the developing nervous system. Cell Death Differ. 2019 Aug;26(8):1501-1515
1	J:283307 Fogarty LC, Song B, Suppiah Y, Hasan SMM, Martin HC, Hogan SE, Xiong J, Vanderluit JL, Bcl-xL dependency coincides with the onset of neurogenesis in the developing mammalian spinal cord. Mol Cell Neurosci. 2016 Dec;77:34-46
1	J:170649 Garcia CM, Huang J, Madakashira BP, Liu Y, Rajagopal R, Dattilo L, Robinson ML, Beebe DC, The function of FGF signaling in the lens placode. Dev Biol. 2011 Mar 1;351(1):176-85
1	J:180905 Kim TH, Kim BM, Mao J, Rowan S, Shivdasani RA, Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme. Development. 2011 Aug;138(15):3225-33
1	J:226395 Lewis AE, Hwa J, Wang R, Soriano P, Bush JO, Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Dev Biol. 2015 Oct 15;406(2):186-95
2*	J:213418 Li D, Sakuma R, Vakili NA, Mo R, Puviindran V, Deimling S, Zhang X, Hopyan S, Hui CC, Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling. Dev Cell. 2014 Apr 28;29(2):233-40
1	J:193698 Li W, Xiong Y, Shang C, Twu KY, Hang CT, Yang J, Han P, Lin CY, Lin CJ, Tsai FC, Stankunas K, Meyer T, Bernstein D, Pan M, Chang CP, Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development. Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1738-43
1*	J:110602 Lin L, Bu L, Cai CL, Zhang X, Evans S, Isl1 is upstream of sonic hedgehog in a pathway required for cardiac morphogenesis. Dev Biol. 2006 Jul 15;295(2):756-63
1	J:152413 Lin W, Metzakopian E, Mavromatakis YE, Gao N, Balaskas N, Sasaki H, Briscoe J, Whitsett JA, Goulding M, Kaestner KH, Ang SL, Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development. Dev Biol. 2009 Sep 15;333(2):386-96
1	J:207089 Liu Y, Harmelink C, Peng Y, Chen Y, Wang Q, Jiao K, CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice. Hum Mol Genet. 2014 Apr 15;23(8):2145-56
1	J:256374 Ogoh H, Yamagata K, Nakao T, Sandell LL, Yamamoto A, Yamashita A, Tanga N, Suzuki M, Abe T, Kitabayashi I, Watanabe T, Sakai D, Mllt10 knockout mouse model reveals critical role of Af10-dependent H3K79 methylation in midfacial development. Sci Rep. 2017 Sep 20;7(1):11922
1	J:335489 Smallwood K, Watt KEN, Ide S, Baltrunaite K, Brunswick C, Inskeep K, Capannari C, Adam MP, Begtrup A, Bertola DR, Demmer L, Demo E, Devinsky O, Gallagher ER, Guillen Sacoto MJ, Jech R, Keren B, Kussmann J, Ladda R, Lansdon LA, Lunke S, Mardy A, McWalters K, Person R, Raiti L, Saitoh N, Saunders CJ, Schnur R, Skorvanek M, Sell SL, Slavotinek A, Sullivan BR, Stark Z, Symonds JD, Wenger T, Weber S, Whalen S, White SM, Winkelmann J, Zech M, Zeidler S, Maeshima K, Stottmann RW, Trainor PA, Weaver KN, POLR1A variants underlie phenotypic heterogeneity in craniofacial, neural, and cardiac anomalies. Am J Hum Genet. 2023 May 4;110(5):809-825
1	J:110698 Stanchina L, Baral V, Robert F, Pingault V, Lemort N, Pachnis V, Goossens M, Bondurand N, Interactions between Sox10, Edn3 and Ednrb during enteric nervous system and melanocyte development. Dev Biol. 2006 Jul 1;295(1):232-49
1	J:160492 Stanchina L, Van de Putte T, Goossens M, Huylebroeck D, Bondurand N, Genetic interaction between Sox10 and Zfhx1b during enteric nervous system development. Dev Biol. 2010 May 15;341(2):416-28
1	J:335428 Sun XL, Chen ZH, Guo X, Wang J, Ge M, Wong SZH, Wang T, Li S, Yao M, Johnston LA, Wu QF, Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development. Dev Cell. 2023 May 8;58(9):744-759.e11
1	J:183402 Taniguchi K, Anderson AE, Sutherland AE, Wotton D, Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway. PLoS Genet. 2012 Feb;8(2):e1002524
1	J:297065 Tao H, Lambert JP, Yung TM, Zhu M, Hahn NA, Li D, Lau K, Sturgeon K, Puviindran V, Zhang X, Gong W, Chen XX, Anderson G, Garry DJ, Henkelman RM, Sun Y, Iulianella A, Kawakami Y, Gingras AC, Hui CC, Hopyan S, IRX3/5 regulate mitotic chromatid segregation and limb bud shape. Development. 2020 Oct 5;147(19):dev180042
1	J:255513 Washausen S, Knabe W, Pax2/Pax8-defined subdomains and the occurrence of apoptosis in the posterior placodal area of mice. Brain Struct Funct. 2017 Aug;222(6):2671-2695
1*	J:340938 Washausen S, Knabe W, Patterns of senescence and apoptosis during development of branchial arches, epibranchial placodes, and pharyngeal pouches. Dev Dyn. 2023 Sep;252(9):1189-1223
1	J:185554 Wu CI, Hoffman JA, Shy BR, Ford EM, Fuchs E, Nguyen H, Merrill BJ, Function of Wnt/beta-catenin in counteracting Tcf3 repression through the Tcf3-beta-catenin interaction. Development. 2012 Jun;139(12):2118-29
1	J:119950 Xu H, Viola A, Zhang Z, Gerken CP, Lindsay-Illingworth EA, Baldini A, Tbx1 regulates population, proliferation and cell fate determination of otic epithelial cells. Dev Biol. 2007 Feb 15;302(2):670-82
1	J:222493 Yamaguchi YL, Tanaka SS, Kumagai M, Fujimoto Y, Terabayashi T, Matsui Y, Nishinakamura R, Sall4 is essential for mouse primordial germ cell specification by suppressing somatic cell program genes. Stem Cells. 2015 Jan;33(1):289-300
1	J:90392 Yang X, Klein R, Tian X, Cheng HT, Kopan R, Shen J, Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway. Dev Biol. 2004 May 1;269(1):81-94
1	J:130854 Yu K, Ornitz DM, FGF signaling regulates mesenchymal differentiation and skeletal patterning along the limb bud proximodistal axis. Development. 2008 Feb;135(3):483-91